Lee E Limbird, PhD Professor of Biochemistry, Department of Life and Physical Sciences, Dean, School of Natural Sciences, Mathematics, and Business Education  Ph.D. in Biochemistry, University of North Carolina at Chapel Hill Office 205 W.E.B. DuBois Hall Email llimbird (at) fisk.edu  Address 1000 17th Ave. N., Nashville, TN, 37208, USA  Phone     (615) 329-1907

Bio

Dr Limbird serves as Dean of the School of Natural Sciences, Mathematics and Business Administration at Fisk University. In addition, she serves as Coordinator of the Pre-Health Professions. Her teaching efforts include Biochemistry and the Biochemistry Laboratory and an upper level graduate/introductory graduate course in Biochemical Approaches to Biomedical Problems that relies on the primary literature to teach methods and discriminating experimental design.

Before joining Fisk University, Dr Limbird served on the faculty of Duke University and for 25 years at Vanderbilt School of Medicine, including her role as Chair of Pharmacology and as the first Associate Vice Chancellor for Research. Dr Limbird’s commitment to undergraduate learning as well as to biomedical research is evident in her service as a member of the Board of Trustees at the College of Wooster in Ohio.

Representative Publications

Textbooks

1. Limbird, L. E., Cell Surface Receptors, a Short Course on Theory and Methods( third edition, 2004). Springer
2. Hardman, J.G., Limbird, L. E .and Gilman, A.G. (editors) Goodman and Gilman’s Pharmacological Basis for Therapeutics. Tenth Edition. McGraw Hill Publishers.

 

Manuscripts

1. Limbird, L. E. The receptor concept: A continuing evolution. Molecular Interventions 4: 326-336, 2005.
2. Wang, Q., Zhao, J., Brady, A.E., Feng, J., Allen, P.B., Greengard, P., and Limbird, L.E. Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors. Science, 304:1940-4, 2004.
3. Tan, C.M., Wilson, M.H., MacMillan, L.B., Kobilka, B.K., and Limbird, L.E. Heterozygous Alpha2A-adrenergic Receptor Mice Unveil Unique Therapeutic Benefits of Partial Agonists. Proc. Natl. Acad. Sci., 99(19):12471-6, 2002.
4. Franowicz, J.S., Kessler, L.E., Borja, C.M., Kobilka, B.K., Limbird, L.E., and Arnsten, A.F. Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. J. Neurosci., 22(19):8771-8777, 2002.
5. MacMillan, L.B., Hein, L., Smith, M.S., Piascik, M.T. and Limbird, L.E. The a_2A- adrenoceptor subtype mediates central antihypertensive effects of a2-agonists. Science 273:801-803, 1996.
6. Surprenant, A., Horstman, D.A., Akbarali, H. and Limbird, L.E. A point mutation of the a₂-adrenoceptor that blocks coupling to potassium but not calcium currents. Science 257:977-980, 1992.